USE Biography


Major: Chemical and Physical Biology

College/Employer: Harvard

Year of Graduation: 2023

Picture of Caleb Shi

Brief Biographical Sketch:

Not Available.

Past Classes

  (Clicking a class title will bring you to the course's section of the corresponding course catalog)

S118: Rewiring the nervous system: introduction to axon regeneration in Splash Splash Spring 2022 (Apr. 23 - 24, 2022)
Salamanders can easily regenerate their nervous systems after injury, including their spinal cord, brain, and retina. Humans, however, lack this regenerative ability in the central nervous system. Injuries to the central nervous system are therefore permanent and can cause paralysis and blindness, among other effects. In this class, we’ll start by exploring the nervous system and the characteristics of some of the cell types contained within it. Then, we’ll take a closer look at why we are unable to regenerate these cell types as well as salamanders can and how that poses a pressing problem in human health. Finally, we’ll talk about some of the research focusing on finding ways to increase the regenerative ability of the human nervous system, including gene therapy through CRISPR and stem cell therapy.